The invention provides compounds of formula (I): ##STR00001## wherein A
and B represent the groups --(CH.sub.2).sub.m-- and --(CH.sub.2).sub.n--
respectively; R.sup.1 represents hydrogen or C.sub.1-6alkyl; R.sup.2
represents hydrogen, halogen, hydroxy, cyano, nitro,
hydroxyC.sub.1-6alkyl, trifluoromethyl, trifluoromethoxy, C.sub.1-6alkyl,
C.sub.1-6alkoxy, C.sub.1-6fluoroalkoxy,
--(CH.sub.2).sub.pC.sub.3-6cycloalkyl,
--(CH.sub.2).sub.pOC.sub.3-6cycloalkyl, --COC.sub.1-6alkyl,
--SO.sub.2C.sub.1-6alkyl, --SOC.sub.1-6alkyl, --S--C.sub.1-6alkyl,
--CO.sub.2C.sub.1-6alkyl, --CO.sub.2NR.sup.5R.sup.6,
--SO.sub.2NR.sup.5R.sup.6, --(CH.sub.2)NR.sup.5R.sup.6,
--(CH.sub.2).sub.pNR.sup.5COR.sup.6, optionally substituted aryl ring,
optionally substituted heteroaryl ring or optionally substituted
heterocyclyl ring; R.sup.3 represents hydrogen, halogen, hydroxy, cyano,
nitro, hydroxyC.sub.1-6alkyl, trifluoromethyl, trifluoromethoxy,
C.sub.1-6alkyl, C.sub.1-6alkoxy, C.sub.1-6fluoroalkoxy,
--(CH.sub.2).sub.pC.sub.3-6cycloalkyl,
--(CH.sub.2).sub.pOC.sub.3-6cycloalkyl, --COC.sub.1-6alkyl,
--SO.sub.2C.sub.1-6alkyl, --SOC.sub.1-6alkyl, --S--C.sub.1-6alkyl,
--CO.sub.2C.sub.1-6alkyl, --CO.sub.2NR.sup.7R.sup.8,
--SO.sub.2NR.sup.7R.sup.8, --(CH.sub.2).sub.pNR.sup.7R.sup.8 or
--(CH.sub.2).sub.pNR.sup.7COR.sup.8; R.sup.4represents hydrogen, hydroxy,
C.sub.1-6alkyl, C.sub.1-6alkoxy, C.sub.1-6fluoroalkoxy, trifluoromethyl,
trifluoromethoxy, halogen, --OSO.sub.2CF.sub.3,
--(CH.sub.2).sub.pC.sub.3-6cycloalkyl, --(CH.sub.2).sub.qOC.sub.1-6alkyl
or --(CH.sub.2).sub.pOC.sub.3-6cycloalkyl; R.sup.5 and R.sup.6 each
independently represent hydrogen, C.sub.1-6alkyl or, together with the
nitrogen or other atoms to which they are attached, form an azacycloalkyl
ring or an oxo-substituted azacycloalkyl ring; R.sup.7 and R.sup.8 each
independently represent hydrogen or C.sub.1-6alkyl; m and n independently
represent an integer selected from 1 and 2; p independently represents an
integer selected from 0, 1, 2 and 3; q independently represents an
integer selected from 1, 2 and 3; or a pharmaceutically acceptable salt
or solvate thereof, with the proviso that the compounds
8-hydroxy-3-methyl-7-phenylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine,
8-hydroxy-7-4-(hydroxyphenyl)sulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine-
, 7-phenylsulfonyl-1,2,3,4-tetrahydroisoquinoline and
7-phenylsulfonyl-1,2,3,4-tetrahydroisoquinoline hydrochloride are
excluded.The compounds are useful in therapy, in particular as
antipsychotic agents.