An isomer, enantiomer, diastereoisomer or tautomer of a compound, represented by formula I:wherein A, B, R.sup.2, R.sup.3, M.sup.1, M.sup.2, M.sup.3, M.sup.4, Y.sup.1 and Z are as defined in claim 1, or a salt thereof, as an inhibitor of HCV NS5B polymerase ##STR00001##

 
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> HCV anti-core monoclonal antibodies

> Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
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