The invention relates to a reverse rotation preventing structure of a centrifugal compressor. The reverse rotation preventing structure of the centrifugal compressor comprises: a discharge pipeline of the centrifugal compressor; a suction pipeline of the centrifugal compressor; a bypass pipeline for connecting the discharge pipeline and the suction pipeline, wherein a predetermined valve is formed thereon; a control means for controlling an operation of the centrifugal compressor; and a detecting means for generating a predetermined signal to the control means if the operation of the centrifugal compressor is suddenly stopped, thereby opening the bypass pipeline.