It is intended to efficiently treat an inflammatory disease without
causing side effects. This object can be achieved by providing a
medicinal composition for treating and preventing an inflammatory disease
and disorders, and disorders caused by the disease and disorders which
contains at least one decoy of NF-.kappa.B or an analogous
transcriptional factor and a pharmaceutically acceptable carrier; and a
method of treating and preventing an inflammatory disease and disorders,
and disorders caused by the disease and disorders which comprises the
step of administering to a patient a composition containing at least one
decoy of NF-.kappa.B or an analogous transcriptional factor and a
pharmaceutically acceptable carrier.