A fluid or powder nasal or oral spray device comprising a body (10), at least one fluid or powder reservoir (20) containing one or more doses of fluid or powder to be dispensed, manually actuated dispenser means (30), such as a pump or a valve, and a manual actuator element (40) adapted for actuating said dispenser means (30) to dispense doses of fluid or powder, said device being characterized in that it further comprises a securing system (50) which is mounted to move between a clutched position, in which said manual actuator element (40) co-operates with said dispenser means (30), and a declutched position, in which said manual actuator element (40) does not co-operate with said dispenser means (30), said securing system (50) being controlled by a parameterizable electronic control unit (60).