The invention provides an organic electro-luminescence element having improved reliability and light emission characteristics and its manufacturing method. The organic electro-luminescence element can include a first substrate, an anode containing a transparent conductive material, a light emitting layer containing an organic electro-luminescence material, cathodes, each including a metal layer and formed in a portion of a forming region for the light emitting layer, antireflection layers, and at least one of a protection layer and a sealing layer. The anode, light emitting layer, and cathodes are stacked on the first substrate in order, the antireflection layers are stacked corresponding to the cathodes, and the at least one of the protection layer and sealing layer can be formed at least between the cathodes and antireflection layers.