A layout modeling system for a transport system to transport articles from a starting position to a plurality of target positions along a transport route includes a plurality of nodes having location information to respectively correspond to the starting position and the target positions at which the articles are transported. The layout modeling system also includes a plurality of links to connect respective nodes along the transport route and having route information to correspond to respective routes between the respective nodes. The route information of each link is updated in real time. Thus, the layout modeling system is capable of minimizing labor and time and setting up an optimum transport route.