A solenoid-operated valve design and method particularly for suited for micro-fluidic applications are disclosed. The solenoid valve contains various structure and features that provide for small dispense volumes, small internal volume, and fast operating speed. Also disclosed is a valve design and method particularly suited for a compact, high-density valve manifold. In a particular embodiment disclosed, the valve uses a diaphragm assembly that ensures zero or little leakage. The solenoid-operated valve further has features allowing for low power consumption.