The present invention relates to a melanin concentrating hormone antagonist compound of Formula I: (I) wherein Ar.sup.1, Ar.sup.2, Ar.sup.3, L.sup.1, L.sup.2 and Q areas defined, or a pharmaceutically acceptable salt, solvate, enantiomer or mixture of diastereomers thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and Related Diseases ##STR00001##