This invention is in the field of a combination comprising a
therapeutically-effective amount of a cyclooxygenase-2 inhibitor, a
5-lipoxygenase inhibitor and an immunosuppressive drug selected from
antiproliferative agents, antiinflammatory-acting compounds and
inhibitors of leukocyte activation. This combination may be used, for
example, to suppress the immune response associated with organ
transplantation, graft versus host disease, and conditions with
underlying autoimmune or inflammatory reactivities or responses.