A probe device is described having a substrate and a die on top of the substrate. The die has an array of stimulation/recording sites having at least one stimulation means and at least one recording means. The substrate comprising the die is folded into a cylindrical shape or a shape with a conical cross-section and, therefore, causes substantially no damage when it is implanted in tissue to be examined or treated, e.g., the brain of a patient in case of a neuro-probe device for use in deep brain stimulation.