Anatomical matching of images acquired by different imaging modalities plays an important role in diagnostic medical imaging. In common medical practice such matching takes place after the acquisition of the data sets containing the information to be matched and while utilizing standard post-processing algorithms. The invention provides a method for the acquisition of anatomically matched images while using the information concerning the position and orientation of the first imaging modality relative to the object. Upon selection of a relevant image from the primary data set acquired by means of the first imaging modality, the co-ordinates which unambiguously define the position of the first imaging apparatus relative to this image are defined. These co-ordinates are made available to the second imaging modality which is adjusted in conformity therewith. The image acquired by the second imaging modality will thus be anatomatically matched with the primary image.