A magnetic resonance imaging scanner (10) includes a main magnet (12), magnetic field gradient coils (16), and one or more radio frequency coils (18). A sequence generator (60, 62, 64, 66) generates an anti-ghosting imaging sequence by dividing k-space into a plurality of profile sub-sets. The sequence generator (60, 62, 64, 66) includes a profile sub-sets ordering processor (60, 62, 64) that orders profiles within each profile sub-set such that the order of profiles within each sub-set is generally different from the orders of the other profile sub-sets, and a profile sub-sets acquisition ordering processor (60, 66) that orders the profile sub-sets in accordance with a selected long-term profiles ordering. The magnetic resonance imaging scanner (10) executes the anti-ghosting imaging sequence to generate imaging data A reconstruction processor (44) reconstructs the generated imaging data into a reconstructed image substantially free of ghosting.