UVB radiation of about 300-310 nm wavelength and UVA radiation of about
380-390 nm wavelength, each of which exists in solar light, induces MMPs
(matrix metalloproteinases) in human skin that degrade the collagen of
the dermal matrix. This degradation contributes to photoaging of human
skin, which can be prevented by blocking these wavelengths of solar
radiation. In contrast, diseases that result in the overproduction of
collagen can be treated by exposing the affected with to radiation having
wavelengths in those regions, for these wavelengths not only induce MMPs
but also inhibit collagen biosynthesis. For lighter skinned people so
affected, the UVA wavelengths are preferred because of the reduced amount
of erythema, whereas dark skinned people can be treated with the UVB
radiation because they generally do not suffer from erythema.