Agents for improving potentcy of the urinary bladder which comprise an
amine compound of non-carbamate-type having an
acetylcholinesterase-inhibiting action. Particularly, crystals of a
tricyclic, condensed, heterocyclic derivative are provided, which possess
an excellent action to inhibit acetylcholinesterase and an action to
improve the excretory potency of the urinary bladder. As an example,
crystals of of
8-[3-[1-[(3-fluorophenyl)-methyl]-4-piperidinyl]-1-oxopropyl]-1,2,5,6-tet-
rahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one or a salt thereof and
pharmaceutical compositions containing them are disclosed.