The present invention relates to compositions for use in analyte
monitoring devices. These compositions are useful to increase the flux of
analyte across skin, tissue or mucosal surfaces. The compositions include
hydrogels and collection reservoir systems comprising ionically
conductive materials. The present invention also includes methods of
making/manufacturing hydrogels or collection reservoir systems,
collection assemblies comprising the hydrogels, electrode assemblies in
combination with the hydrogels or collection reservoir systems, and
methods of using the same.