The invention includes methods for prophylaxis of at least one of infection with HIV/AIDS and venereal diseases, grippe/influenza. The method includes use of materials, in solution, cream, gel and/or tablet form, which possess virucidal and bactericidal characteristics. The method includes applying such materials to a mammal's skin and/or mucous membranes in solution and/or cream or gel form. Also provided is a method applying such materials to the mouth and/or throat and nose for inhalation for prevention of and/or treatment of grippe and influenza. One such solution is an aqueous solution that includes about 0.1 to about 0.3 percent by weight pantoprazole or a derivative thereof, about 2 percent to about 4 percent by weight sodium chloride, about 0.1 percent to about 5 percent by weight sodium hydrocarbonate, and 0 percent to about 1 percent sodium tetraborate. Creams or gels including pantoprazole may also be used.