The present invention concerns a compound consisting of RNA, in particular
RNA extracted from yeast, a pharmaceutical composition comprising such
RNA and a method for the treatment of inflammatory and
inflammatory-related disorders comprising administering to a patient in
need of such treatment a pharmaceutical composition comprising an amount
effective to ameliorate the symptoms of inflammation or
inflammatory-related disorder of ribonucleic acid and a pharmaceutically
acceptable vehicle, carrier, or diluent. The exogenous yeast RNA used in
the present invention has a pronounced membrane-stabilizing action in a
wide range of concentrations. At the same time, yeast RNA normalizes
metabolism of arachidonic acid and levels of its key metabolites,
thromboxane and leukotriene. Its anti-inflammatory action is accompanied
by normalization of the activity of NO-synthetase and anti-oxidant
activity.