The present invention provides a method for diagnosing and detecting
cancer. The present invention provides one or more proteins or fragments
thereof, peptides or nucleic acid molecules differentially expressed in
cancer (podocalyxin) and antibodies that bind podocalyxins. The present
invention provides that podocalyxins are used as targets for screening
agents that modulate podocalyxin activities. Further the present
invention provides methods for treating diseases associated with
podocalyxin expression.