An intervertebral prosthesis for insertion between adjacent vertebrae includes a first prosthesis plate and a second prosthesis plate. The first and second prosthesis plates each comprise a midline, an engagement surface to engage a first vertebra and a bearing surface disposed opposite the engagement surface. The bearing surfaces of the first and second plates are arranged to cooperate to form an articulate joint. A first region of serrations is disposed on the engagement surface of the first plate on one side of the midline of the first plate, and a second region of serrations is disposed on the engagement surface of the first plate on an opposite side of the first plate midline. Each region comprises at least several serrations, and each serration comprises a base attached to one of the plates and tapers from the base to a tip.