A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following formula, ##STR00001## where R1 is a C.sub.13-17 alkyl, and R2 and R3 are each independently H or --CH.sub.3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.