A surgical instrument for driving a threaded member into a substrate generally includes a drive shaft, a support member and a biasing member. The drive shaft includes a distal end portion configured for releasable engagement with the threaded member. The drive shaft is axially coupled with the support member in a manner allowing relative axial displacement therebetween, with the drive shaft rotatably coupled with the support member such that rotation of the support member correspondingly rotates the drive shaft. The biasing member is coupled between the support member and the drive shaft and is configured to transmit an axial force from the support member to the drive shaft as the threaded member is driven into the substrate, and with the axial force being limited as a distal end of the support member is engaged against a surface adjacent the substrate to correspondingly limit an axial force exerted onto the threaded member by the drive shaft to facilitate rotational disengagement of the drive shaft from the threaded member.

 
Web www.patentalert.com

> Non-glycosylated human alpha-fetoprotein, methods of production, and uses thereof

~ 00314