Unhandled operation of a program instruction of a first instruction set, such as a Java bytecode, is detected. Instead of invoking a mechanism for directly dealing with that unhandled operation, one or more instructions from a second instruction set, such as ARM instructions, are instead used to emulate the instruction that was subject to the unhandled operation. If these instructions of the second instruction set are also subject to unhandled operation, then the mechanisms for dealing with unhandled operation within that second instruction set may be invoked to repair that operation. This approach is well suited to dealing with unhandled operation of variable length instructions being interpreted with a processor core having a native fixed length instruction set. In particular, prefetch aborts and unhandled floating point operations may be conveniently dealt with in this way.