A vacuum grooming tool is disclosed that includes a vacuum nozzle attachable to a vacuum source and has a hollow body with a mouth opening. A grooming device selected from a variety of standard animal grooming hand tools, such as a shedding blade, rake, or de-matting tool, may span the mouth opening. The grooming device is positioned such that the airflow created by the vacuum source flows over at least one side of the grooming device. A vacuum cleaning tool for removing any animal hair from a grooming tool is also disclosed. A vacuum plenum of the cleaning tool is attachable to a vacuum source and has an opening for cleaning the grooming tool in one pass. The cleaning tool can be mounted on a stationary support and may also include a pivot-action mechanism that connects the vacuum grooming tool or the cleaning tool to the vacuum source.

 
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> Animal model for identifying agents that inhibit or enhance CTLA4 signaling

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