System and method for using a graphical user interface (GUI) to generate a measurement task specification (MTS) for performing a measurement task. The measurement task includes measurement and/or signal generation. A measurement task specifier presents a GUI which guides a user in specifying the measurement task. The GUI presents a plurality of GUI elements, e.g., panels, for specifying a plurality of parameters for the measurement task, including measurement type, devices, channels, timing, and/or triggering. The GUI receives user input indicating values for the parameters, and may provide default values for at least some of the parameters. The GUI stores the parameter values in a memory, analyzes the parameter values, and generates the MTS in response to the analyzing. The MTS is then useable to produce a program which implements the measurement task. The specifier may programmatically generate the program, e.g., a graphical program, which is executable to perform the task.