A system, which includes a processor that includes a plurality of cores, generates an address translation when there is a miss in a translation lookaside buffer (TLB). A hypervisor utilizes a translating load instruction that upon execution on the processor generates a data portion of a TLB entry. Execution of the translating load instruction utilizes information from a real-to-physical address translation table entry and information provided in the call to the translating load instruction to synthesize the data portion of a new virtual-to-physical translation table entry.