A composition comprising, per liter of aqueous solution, from 30 to 350 g
polyethylene glycol, from 3 to 20 g of an ascorbic acid component
selected form the group consisting of ascorbic acid, a salt of ascorbic
acid, or a mixture thereof, an alkali metal or alkaline earth metal
sulphate, preferably from 1 to 15 g thereof, and optionally one or more
electrolytes selected from sodium chloride, potassium chloride, and
sodium hydrogen carbonate, and preferably also comprising flavorings, is
effective in cleansing the gut in preparation for a endoscopy, especially
colonoscopy. It is safer than conventional sodium phosphate-based gut
cleansing compositions, and hence can be used for patients who would be
at risk with sodium phosphate-based compositions, and is better tolerated
than conventional PEG-based compositions, leading to better patient
compliance and enabling effective out-patient use.