The present invention relates to method for the isolation of at least one biologically active substance from an industrial dairy by-product or waste flow, comprising--selecting at least one industrial dairy waste or by-product flow containing at least one biologically active substance;--bringing the at least one industrial dairy waste or by-product flow into contact with at least one solid insoluble support material for sufficient time to cause the at least one biologically active substance to selectively adsorb on said support material;--recovering the insoluble solid support material carrying the adsorbed at least one biologically active substance.