A psychotropic agent, analgesic and/antiinflammatory agent, or health food which is safe even when taken for an extended period of term, comprising as an effective ingredient a benzylisoquinoline derivative represented by general formula (I): or a bisbenzylisoquinoline derivative represented by general formula (II): or a pharmaceutically acceptable salt thereof.

 
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> ORALLY ADMINISTERED AGENT FOR IMPROVING SKIN CONDITION

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