The disclosed embodiments of the present invention are used to permanently disable or destruct an RFID so that it is no longer possible to read some or all of the data encoded on the RFID tag. In one method for disabling data on a radio frequency identification (RFID) tag, an RFID tag is identified and its identity is confirmed. Verification that a prerequisite event has occurred is obtained, occurrence of which is required prior to disablement of the data. A destruct instruction is transmitted to the RFID tag. The RFID tag verifies that the destruct instruction is valid and disables the data upon verifying validity of the destruct instruction. The tag may disable the data by erasing the data, disabling the data, auto-destructing, or performing any operation that makes the data unreadable.