Methods and compositions for producing flowable compositions, e.g. pastes,
that set into calcium phosphate products are provided. In the subject
methods, dry reactants that include a calcium source and a phosphate
source are combined with setting fluid to produce the flowable
composition. A feature of the subject methods is that the dry reactants
include a particulate calcium and/or phosphate reactant having a mean
particle size of less than about 8 .mu.m and narrow size distribution.
Also provided are the compositions themselves as well as kits for use in
practicing the subject methods. The subject methods and compositions
produced thereby find use in a variety of applications, including the
repair of hard tissue defects, e.g., bone defects.