Disclosed is a method for preparing
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol,
pharmaceutically acceptable salts, and pharmaceutically acceptable
solvates thereof, such as the
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol
hydrochloride salt via dynamic kinetic resolutions.