A system and method are provided for automatically developing and implementing, a comprehensive customized care plan for a patient, to address all of the patient medical and non-medical (e.g., social, quality-of-life, personal) needs, utilizing a wide variety of information: both gathered both personally from a patient by a medical professional and also collected automatically by one or more telemedicine systems. The system and method of the present invention also continually re-assess and dynamically modify the comprehensive care plan, and additionally enable a wide variety of services and benefits to be made available to the patients in a manner automatically customized for their specific needs, with the offered services and benefits being dynamically adjusted as the patient needs change or evolve. In addition, the inventive system provides platform-independent capabilities so that diagnostic systems and devices from various vendors may be freely mixed to provide patients with customized diagnostic monitoring at the lowest possible cost.