A new and distinct cultivar of Chrysanthemum plant named `Yomistique`, characterized by its uniform, compact and somewhat outwardly spreading plant habit; strong and freely branching growth habit; dense and bushy appearance; dark green-colored foliage; uniform flowering response and habit; typically grown as a spray-type; very early flowering habit; small daisy-type inflorescences with elongated oblong-shaped ray florets; purple-colored ray florets with light yellow green towards the base; and excellent postproduction longevity with plants maintaining good substance and color for about four to five weeks in an interior environment.