Human chemokine polypeptides and DNA (RNA) encoding such chemokine
polypeptides and a procedure for producing such polypeptides by
recombinant techniques is disclosed. Also disclosed are methods for
utilizing such chemokine polypeptides for the treatment of leukemia,
tumors, chronic infections, autoimmune disease, fibrotic disorders, wound
healing and psoriasis. Antagonists against such chemokine polypeptides
and their use as a therapeutic to treat rheumatoid arthritis, autoimmune
and chronic inflammatory and infective diseases, allergic reactions,
prostaglandin-independent fever and bone marrow failure are also
disclosed. Diagnostic assays for identifying mutations in nucleic acid
sequence encoding a polypeptide of the present invention and for
detecting altered levels of the polypeptide of the present invention are
also disclosed.