Techniques for performing power control of multiple channels sent using multiple radio technologies are described. The transmit power of a reference channel, sent using a first radio technology (e.g., CDMA), is adjusted to achieve a target level of performance (e.g., a target erasure rate) for the reference channel. The transmit power of a data channel, sent using a second radio technology (e.g., OFDMA), is adjusted based on the transmit power of the reference channel. In one power control scheme, a reference power spectral density (PSD) level is determined based on the transmit power of the reference channel. A transmit PSD delta for the data channel is adjusted based on interference estimates. A transmit PSD of the data channel is determined based on the reference PSD level and the transmit PSD delta. The transmit power of the data channel is then set to achieve the transmit PSD for the data channel.