Disclosed is a dynamically configurable threat scanning machine management system that utilizes a network to connect threat scanning machines with a central control computer. The central control computer can transmit, among other things, operational software and threat profiles to the threat scanning machines, while the threat scanning machines can transmit, among other things, images and performance data to the central computer. The threat scanning machine management system can be arranged in a hierarchical manner, which enables threat scanning machines at various locations to be connected into regional, national or international control centers for greater management efficiency. The network may be wireless and the control computer may be portable, enabling a supervisor to remotely manage the threat scanning machines while remaining mobile about the facility, or elsewhere. Additionally, the threat scanning machine management system can be accessed and monitored remotely from a web browser via secure Internet access.