A guide wire, which has excellent follow-up characteristics, sufficients contrasting characteristics and flexibility at a distal end portion thereof and high elasticity at a proximal end portion thereof, includes a core wire, and a coil wire provided on the distal end portion of this core wire coaxially therewith. The coil wire is formed by winding a plurality of wires, which are formed of different constituent materials and placed side by side on a plane, uniformly in an axial direction of the core wire so that the wires are adjacent to each other on the same plane.