An elastomeric glove that contains zones of differing water vapor transmission rates is provided. The glove contains at least one liquid and vapor impermeable zone, i.e., "moisture-impermeable" zone. Such moisture-impermeable zones generally have a WVTR of less than about 1500 g/m.sup.2/24 hours. Further, the glove also contains at least one liquid-impermeable, but vapor-permeable zone, i.e., "breathable" zone. Such breathable zones generally have a WVTR of at least about 250 g/m.sup.2/24 hours. As a result, the glove may sufficiently inhibit liquids and moisture from contacting the hand during use, and allow water vapor that would otherwise accumulate on the skin of a user to escape from the glove, thereby enhancing the comfort of the user's hands during long periods of use.