A system for detecting access to an article, including an RFID tag, a reader detecting the RFID tag via wireless communication, and a container including conductive material is described. The container encloses the article. The conductive material surrounds the RFID tag and substantially prevents wireless communication between the RFID tag and the reader unless the container is opened. Detection of the RFID tag may indicate that the container has been opened or the article has been accessed. A host computer may be notified of the detection and may receive from the RFID tag information associated with the article for inventory and accounting purposes.