A system and method for determining a carrier layout using cornered chip-to-chip input/output is presented. Each of a plurality of individual integrated circuit carriers communicatively interfaceable through cornered input/output ports is oriented at a uniform rotation relative to an edge of a carrier layout. Each carrier defines a set of rectilinear edges. Each carrier is placed juxtaposed at an open corner to at least one other carrier within a rectilinear lattice topologically arranged in the carrier layout to substantially minimize Hamming distances between each of the carriers.