The present invention provides a three-piece solid golf ball, of which flight distance is improved by accomplishing high launch angle and low spin amount in initial flight performance, while maintaining soft and good shot feel when hitting at low head speed. The present invention relates to a three-piece solid golf ball comprising a center, intermediate layer and cover, wherein the center has a deformation amount of 3.5 to 5.5 mm, a hardness difference (H.sub.S-H.sub.C) from a central point hardness (H.sub.C) of 10 to 40 and a surface hardness H.sub.S of 36 to 50, base resins of the intermediate layer and cover are formed from thermoplastic resin, and the intermediate layer has a hardness H.sub.M of 36 to 50, the cover has a hardness H.sub.L of 58 to 69, a hardness difference (H.sub.S-H.sub.M) is 0 to 15, and (H.sub.L-H.sub.M) is 10 to 28.