The present invention provides the use of nucleic acid sequences and/or
amino acid sequences in the preparation of a vaccine for the protection
of fish against infectious salmon anaemia virus. Specifically, such
vaccines contain at least one nucleic acid sequence which is derived from
ISAV or synthetically prepared analogues thereof, or substantially
homologous sequences. These nucleic acid sequences are transcripted and
translated into peptide sequences which are incorporated into a
vaccination strategy to induce and immune response to the surface
antigens of ISAV and therefore ISAV itself. Therefore both the use of a
vaccine against ISAV, and the incorporation of peptide sequences is
herein described.