Compositions of the invention include composites comprising a biomaterial
having compounds thereon with enhanced cell binding with respect to
collagen. These composites are useful for soft and hard tissue repair or
reconstruction and for in vitro uses. Suitable compounds with enhanced
cell binding include synthetic peptides that mimic the conformation
necessary for recognition and docking of collagen binding species (such
as cell surface receptors for collagen and fibronectin) and have the
amino acid residues -Ile-Ala-folded in a .beta.-bend.