A compound represented by the following formula (I) ##STR00001## wherein R.sup.1 is a lower alkyl group, R.sup.2 is a hydrogen, a halogen, a cyano group, a lower alkyl group or a lower alkoxy group, and n is 0 or 1, which has a calpain inhibitory activity, is provided.

 
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> Benzamidine derivatives having anti-inflammatory and immunosuppressive activity

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