A system and method providing low-power operation in a multimode communication device. Various aspects of the present invention may, for example, include at least one radio module that is adapted to communicate in a plurality of communication modes. The at least one radio module may also be adapted to operate in at least a first power-save mode. At least one module may, for example, be adapted to analyze at least one non-informational aspect of a signal (e.g., a received radio signal) to determine whether a first communication network corresponding to a first communication mode of the plurality of communication modes might be available. The at least one module may then, for example, be adapted to determine, based at least in part on the determined availability of the first communication network, whether to operate the at least one radio module in a respective mode other than the first power-save mode.