A disk drive support assembly has a clamp arrangement for releasably clamping a disk drive to a massive block. The clamp arrangement may be an inflatable actuator that is operable to clamp the disk drive to the block via a disk drive carrier. Various clamp assemblies for clamping a disk drive to a substrate, such as a disk drive carrier, are also disclosed. A disk drive carrier that can be adapted for use with different types of disk drive is also disclosed. Such disk drives include those that provide for electrical and/or data connections under the disk drive, those that provide for electrical and/or data connections at the rear of the disk drive, and those that have their own so-called product card associated therewith.