A skin rejuvenating supplement composition for treating age spots, darkening of the skin, dry skin, calcium amino acid deficiencies, osteoporosis and eye site deficiencies. The composition contains 100 to 1,500 mg of pearl powder, 0.6 to 50 .mu.kg Vitamin D, 1.5 to 20.0 mg of astaxanthin and 20 to 750 mg of bilberry extract. The composition can be administered in a tablet, also containing glycerol in an amount of about 500 mg, once or two times per day.