The invention relates to aqueous dispersions, comprising particles based
on a magnetic iron oxide with dimensions of .ltoreq.20 nm, the surface of
which is modified by the grafting of aminated groups R with a covalent
bonding to the surface of said particles, wherein the isoelectronic point
of particles with such a modified surface is .gtoreq.10. The invention
further relates to a method for production of said aqueous suspensions
and a method for modification of the surface of the particles present in
said dispersions, in particular, by the immobilisation of polysaccharides
such as dextrans, particularly for the formulation of magnetic
compositions which may be administered in vivo and in particular for the
formulation of injectable compositions of contrast agents for MRI.