We describe a method to inhibit cell division of hyperproliferative cells,
typically cancer cells, by introducing inhibitory RNA (RNAi) into said
cells to ablate mRNAs that encode polypeptides involved in cellular
processes and including RNAi molecules and vectors including
transcription cassettes encoding said RNAi molecules. By application of
said RNAi molecules to cancers in vivo it is possible to effect a
treatment whereby the cancer cells are killed or otherwise eliminated.